Direct Identification of Anastomotic leakage with Microdialysis in Abdominal surgery

Direct Identification of Anastomotic leakage with Microdialysis in Abdominal surgery - DIAMAnt-study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31648

Enrollment

202

Registered

2008-10-31

Start date

2009-02-11

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

maagdarmstelsel diagnostiek Anastomotic leakage peritonitis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Planned esophagectomy and gastric pull-up for preoperative T1-3N0-1M0 esophagus carcinoma, pancreaicoduodenectomy for resectable pancreatic or biliairy neoplasm, sigmoid or rectumresection for adenoma or carcinoma. Patients are capable of making decisions autonomously. ASA class 1,2 and 3.

Exclusion criteria

Exclusion criteria: ASA 4-5

Design outcomes

Primary

Measure	Time frame
Determination of near anastomotic postoperative levels of pyruvate, lactate, glycerol and glucose by micodialysis after esophagectomy and gastric pull-up. Determination of postoperative levels of pyruvate, lactate, glycerol and glucose by micodialysis of peritoneal fluid after sigmoid or rectum resection. Determination of near anastomotic postoperative pyruvate, lactate, glycerol and glucoselevels by micodialysis after pancreaticoduodenectomy.	—

Measure

Time frame

Determination of near anastomotic postoperative levels of pyruvate, lactate, glycerol and glucose by micodialysis after esophagectomy and gastric pull-up. Determination of postoperative levels of pyruvate, lactate, glycerol and glucose by micodialysis of peritoneal fluid after sigmoid or rectum resection. Determination of near anastomotic postoperative pyruvate, lactate, glycerol and glucoselevels by micodialysis after pancreaticoduodenectomy.

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Secondary

Measure	Time frame
Determination of postoperative levels of pyruvate, lactate, glycerol and glucose in case of anastomotic leakage after sigmoid or rectum resection. Correlation of microdialysis values to clinical and diagnostic findings.	—

Countries

Netherlands

Outcome results