Sensitivity of cholangioscopy directed biopsies versus brush cytology in patients with malignant bileduct stenosis

Sensitivity of cholangioscopy directed biopsies versus brush cytology in patients with malignant bileduct stenosis - (COCYSTENS-study)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31613

Enrollment

Registered

2008-04-14

Start date

2008-05-08

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bileduct stenosis bileduct stricture

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age >= 18 year icterus (bilirubine >2xULN) Cholestasis (GGT or alk fos >2xULN) dilated bile ducts on imaging with abdominal ultrasound, CT, or MRI

Exclusion criteria

Exclusion criteria: Distal CBD stenosis Clinical conditions that do not allow ERCP with sphincterotomy such as uncorrectable coagulopathies High suspicion of common bile duct stones Patients unable or not willing to give informed consent

Design outcomes

Primary

Measure	Time frame
1. The difference in sensitivity between brush cytology en cholangioscopic directed biopsy for detection of patients with malignant biliary stricture. 2. Cholangioscopic aspect of stricture	—

Secondary

Measure	Time frame
Duration of examination	—

Countries

Netherlands

Outcome results