cefazolin concentrations in plasma and interstitial fluid
Conditions
Interventions
None listed
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: · Age => 18 years · Surgical procedures: hip of knee surgery osteotomy surgery to cruciate ligaments neurosurgery · Cefazolin prophylaxis (1 gram) · Signed informed consent
Exclusion criteria
Exclusion criteria: · Age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameters/endpoints: serum and interstitial fluid concentration of cefazolin at specific timepoints before and during surgery until 2 hours after woundclosure. | — |
Secondary
| Measure | Time frame |
|---|---|
| to implement the results in daily practice | — |
Countries
Netherlands
Outcome results
None listed