total knee replacement
Conditions
Interventions
Surgery will be performed as usual. Only just before wound closure the fibrin
sealant will be spayed over the wound surface.
Sponsors
Sanquin Bloedbank
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: •patients who will undergo knee replacement susrgery •Age, minimum of 18 years •Gender, man or woman •Admission of the patient after informed consent
Exclusion criteria
Exclusion criteria: •Liver failure •Congenital or acquired coagulation disorders •Patients who need coumarine derivatives (acenocoumarol or fenprocoumon)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total volume of fluid in the drains at 6h post-operative. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints: total volume of fluid in the drains at 24h post-operative, amount of blood transfused, size of the knee, amount of pain and mobility (quality of life) after surgery, length of stay in hospital, adverse events, satisfaction with fibrin sealant as used by the physician. | — |
Countries
Netherlands
Outcome results
None listed