cancer malignancy
Conditions
Interventions
Healthy volunteers who are willing to participate and who signed informed
consent will be injected with a one time subcutaneous injection of filgrastim
of 0.03 µg or saline 0.9% (1ml). Patients will
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1.The volunteer must be >= 18 years of age 2.The volunteer must be healthy meaning having no relevant medical history and havind no clinical signs of intercurrent infection at physical exam at start of the study 3.The volunteer mustn*t have known hypersensitivity to the to be administrated drugs (filgrastim®) 4.The patient must have given written informed consent 5. women wild child bearing potential must have a negative serum pregnancy test 48 hrs before start
Exclusion criteria
Exclusion criteria: Any other condition by which the patient doesn*t meet the inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary objective is: To determine whether a single subcutaneous injection of G-CSF induces an immediate (within six hours) release of bone marrow progenitor cells in healthy volunteers. | — |
Secondary
| Measure | Time frame |
|---|---|
| nvt | — |
Countries
Netherlands
Outcome results
None listed