Modelling of saliva gentamicin concentrations in neonates receiving gentamicin treatment

Modelling of saliva gentamicin concentrations in neonates receiving gentamicin treatment - Gentamicin in saliva of neonates

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31541

Enrollment

Registered

2008-03-18

Start date

2008-03-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal infection Neonatal sepsis

Interventions

None listed

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: •Term or preterm infants with a postnatal age

Exclusion criteria

Exclusion criteria: •Infant suspected of or suffering from necrotizing enterocolitis

Design outcomes

Primary

Measure	Time frame
Description of the concentration-time profile of saliva gentamicin levels in neonates.	—

Secondary

Measure	Time frame
The development of a valid population PK model which can predict serum gentamicin concentrations based on gentamicin concentrations in saliva. If a fitting model is obtained: assessment of the dosing advice that a hospital pharmacist would come to based on serum gentamicin concentrations predicted by the model.	—

Countries

Netherlands

Outcome results