The incidence of endothelial dysfunction and atherogenesis in hemophilia patients with obesity: the Idaho-study

The incidence of endothelial dysfunction and atherogenesis in hemophilia patients with obesity: the Idaho-study - The Idaho study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31530

Enrollment

160

Registered

2008-05-27

Start date

2008-01-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hemofilie, atherosclerose, endotheeldysfunctie, obesitas bleeders' disease cardiovascular disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Haemophilia A patients (obese or normal weight) All haemophilia patients are male All subject are 18 years or older

Exclusion criteria

Exclusion criteria: pre-existing cardio-vascular disease

Design outcomes

Primary

Measure	Time frame
Endothelial function and degree of atherosclerosis will be compared in the four groups. The degree of inflammation, platelet aggregation, fibrin formation, and fibrinolysis will also be assessed in the four different groups.	—

Secondary

Measure	Time frame
We will also investigate the amount of bleeding complications and analyse the influence of obesity on this outcome.	—

Countries

Netherlands

Outcome results