Brain activity, corticospinal integrity and fatigue in MS patients

Brain activity, corticospinal integrity and fatigue in MS patients - Fatigue in MS patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31495

Enrollment

Registered

2008-11-21

Start date

2008-03-11

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MS multiple sclerosis white matter disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients suffering from Multiple Sclerosis Right handedness Informed consent

Exclusion criteria

Exclusion criteria: neurological disorders other than MS, fMRI exclusion criteria (e.g. metal implants)

Design outcomes

Primary

Measure	Time frame
1) Abduction force of index finger, 2) EMG of the abductor of the first dorsal interosseus (FDI), 3) The amplitude of the twitch force during a maximal contraction, 4) The intensity of brain activity during submaximal and maximal, fatiguing contractions, 5) Amplitude and latency of the MEP and duration of the silent period.	—

Secondary

Measure	Time frame
None	—

Countries

Netherlands

Outcome results