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gene-person-environment interaction in resilience against depression

gene-person-environment interaction in resilience against depression - The etiology of resilience against depression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON31494
Enrollment
120
Registered
2007-09-26
Start date
2008-01-07
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression mood disorder

Interventions

The experimental group receives 8 weeks of mindfulness training by an experienced trainer in addition to their normal treatment, if any. Sessions are weekly (2,5 hours a session) and subjects receiv

Sponsors

Universiteit Maastricht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: i) previous episode of major depressive disorder ii) residual symptoms: score >7 on the Hamilton Rating Scale for Depression (HAM-D17), for at least two weeks.

Exclusion criteria

Exclusion criteria: i) meeting criteria for current major depressive disorder

Design outcomes

Primary

MeasureTime frame
The increase in reward experience in daily life, whereby reward experience is conceptualised as the effect of small daily life positive events on positive mood state. Since ESM measurements are performed 10 times a day for 6 days, there will be a maximum of 60 measurements within each subject concerning effects of positive events on positive mood state in the flow of daily life.

Secondary

MeasureTime frame
- The association between increase in reward experience and decrease in depressive symptomatology - The association between individual variation in reward experience (or increase in reward experience) and genetic variation in polymorphisms related to the brain reward system. - The association between increases in reward experience and decreases in risk of future relapse in depression

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)