Redistribution of pulmonary blood flow as a cause for the progression of pulmonary hypertensionin after chronic thrombo-emboli.

Redistribution of pulmonary blood flow as a cause for the progression of pulmonary hypertensionin after chronic thrombo-emboli. - Cause of progression in chronic thromboembolic pulmonary hypertension

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31465

Enrollment

Registered

2008-02-14

Start date

2008-02-18

Completion date

Unknown

Last updated

2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic thromboembolic pulmonary hypertension AND increased pressure in pulmonary vessels due to bloodclots

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Mean pulmonary artery pressure (mPAP) > 25 mmHg. - Specific features of chronic thromboembolism on pulmonary angiography as assessed by radiologist(s). - No previous treatment of oral anticoagulation

Exclusion criteria

Exclusion criteria: - Presence of systemic inflammation. - Patients with pulmonary hypertension associated with collagen vascular disease, congenital heart disease, pulmonary venous hypertension, left heart failure, hypoxemic lung disease (COPD) - bad kidney function (creatinin > 120)

Design outcomes

Primary

Measure	Time frame
Changes assessed by MRI between obstructed and non-obstructed regions of the lungs by means of: - Pulmonary blood volume - Pulmonary blood flow - Mean transit time - Pulmonary vascular resistance	—

Countries

Netherlands

Outcome results