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Effects of osteotomies around the knee on cartilage glycosaminoglycan content using dGEMRIC non-invasive imaging

Effects of osteotomies around the knee on cartilage glycosaminoglycan content using dGEMRIC non-invasive imaging - dGEMRIC and osteotomies

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON31458
Enrollment
10
Registered
2007-12-04
Start date
2008-04-17
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

joint degeneration osteoarthritis

Interventions

None listed

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Osteoarthritis of the knee Planned osteotomy above or below the knee

Exclusion criteria

Exclusion criteria: Contra-indications for MRI scanning, using Gadolinium as a contrast agent

Design outcomes

Secondary

MeasureTime frame
Above mentioned outcomes will be correlated to questionnaires, measuring clinical effectiveness of the procedure (KOOS, VAS, Knee Society Scale).

Primary

MeasureTime frame
The measurement of the average T1-value will be performed measuring the distance from the location with the worst T1-signal to the center axis of the upper and lower limb. Further, changes in intensity of T1 signal will be measured to evaluate progression or decrease of cartilage damage.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)