Psychosis Schizophrenia
Conditions
Interventions
None listed
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. between 18 and 50 years 2. native speakers of Dutch 3. able to read and understand the inform consent 4. patients: (a) Diagnosed with a non - affective psychosis (b) first contact with a psychiatric institution because of psychotic symptoms 10 years maximum 5. first-degree relatives: brother or sister of the patient who was diagnosed with a non-affective psychosis 6. healthy controls: (a) never diagnosed with a lifetime diagnosis of non-affective psychosis; (b) none of first-degree relatives were diagnosed with a psychotic disorder
Exclusion criteria
Exclusion criteria: 1. mental retardation (IQ
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reaction times in the different conditions will be compared between the three groups. Mean amplitude and latency of the N400, P3 and the LPP ERP components will be compared between the different conditions and between the groups. Source localization will be conducted for each condition and each group. All words or combinations of words from the participants will be analysed if it is a existing word of the narratives or if it is a non-existing word of the narratives. The amount of words, and the longest phrase - counted as the number of words reported by the participant - comprised the length of speech illusion (LSI score). Correlations between reaction times and ERP components of the different conditions and the level of positive and negative symptoms will be investigated. | — |
Secondary
| Measure | Time frame |
|---|---|
| / | — |
Countries
Netherlands
Outcome results
None listed