PROgnosis in Post Anoxic Coma II: PROPAC II

PROgnosis in Post Anoxic Coma II: PROPAC II - PROPAC II

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31448

Enrollment

300

Registered

2007-10-25

Start date

2007-11-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coma after resuscitation postanoxisch coma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients > 18 years of age who are treated with induced hypothermia after non-traumatic circulatory arrest

Exclusion criteria

Exclusion criteria: Pre-existing disease with reduced life expectancy (

Design outcomes

Primary

Measure	Time frame
NSE level which can be used as a good predictor (false positive rate van 0%) for a poor outcome in patients with postanoxic coma who are treated with hypothermia. Neurological outcome will be assessed after one week, one month and six months. Outcomes will be documented using the Glasgow Outcome Scale (GOS). Poor outcome will be defined as death, vegetative state, or severe disability (GOS scores 1-3) six months after CPR.	—

Measure

Time frame

NSE level which can be used as a good predictor (false positive rate van 0%) for a poor outcome in patients with postanoxic coma who are treated with hypothermia. Neurological outcome will be assessed after one week, one month and six months. Outcomes will be documented using the Glasgow Outcome Scale (GOS). Poor outcome will be defined as death, vegetative state, or severe disability (GOS scores 1-3) six months after CPR.

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Secondary

Measure	Time frame
Value of SSEP investigations performed during mild hypothermia in predicting poor outcome in postanoxic coma.	—

Countries

Netherlands

Outcome results