Pilot study: Gastric emptying with 13C breath test

Pilot study: Gastric emptying with 13C breath test - Gastric emptying

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31414

Enrollment

Registered

2007-11-05

Start date

2007-10-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anorexia verlies van eetlust

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Apparently healthy, as judged by the subject Age: Young adults: 18-30 year, Older adults: 60-80 year Used to eating breakfast (> 5 times per week)

Exclusion criteria

Exclusion criteria: Weight change of >5kg during the last 2 months Being on a weight loss diet On a prescribed diet that interferes with the study foods Bowel or stomach disorder Diabetes or thyroid disorder Food intolerance or allergy for foods that are provided during the study

Design outcomes

Primary

Measure	Time frame
The main study outcome is gastric emptying (and the variation in that measurement). Gastric emptying will be measured with a non-invasive breath test. The subject will come in fasting state to the research centre and ingest the test product which is labelled with 13C. The test foods consist of 2 experimental cooked foods, differing in energy content. Each food will be measured in duplicate. Breath samples will be collected before consumption of the food and at 15 minute intervals during 4-6 hours. Breath samples will be analyzed on concentration of 13C. 13C recovery (T1/2 and Tlag) will be used as a measure for gastric emptying.	—

Measure

Time frame

The main study outcome is gastric emptying (and the variation in that measurement). Gastric emptying will be measured with a non-invasive breath test. The subject will come in fasting state to the research centre and ingest the test product which is labelled with 13C. The test foods consist of 2 experimental cooked foods, differing in energy content. Each food will be measured in duplicate. Breath samples will be collected before consumption of the food and at 15 minute intervals during 4-6 hours. Breath samples will be analyzed on concentration of 13C. 13C recovery (T1/2 and Tlag) will be used as a measure for gastric emptying.

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Secondary

Measure	Time frame
Secondary, appetite and wellbeing ratings will be measured during the test (Visual Analogue Scales).	—

Countries

Netherlands

Outcome results