PETscan imaging for objectivation of cortical hyperactivity in tinnitus patients

PETscan imaging for objectivation of cortical hyperactivity in tinnitus patients - PETscan for chronic tinnitus

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31403

Enrollment

Registered

2007-11-20

Start date

2008-01-31

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

noise in the head tinnitus

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Chronic tinnitus, > 3 months, perceived in the head, not lateralized, constant in presence. Right-handed

Exclusion criteria

Exclusion criteria: Presence of any major medical, neurological or psychiatric diagnoses now or in the past, specific epilepsy, severe head injury or previous cranial neurosurgery. Participation in a PET study in the year prior to this study. Radiological workers. Use of drugs or medications that reduce cortical excitation such as anticonvulsants, benzodiazepines or other sedatives. Pregnancy.

Design outcomes

Primary

Measure	Time frame
The main study parameter will be the cortical hyperactivity in tinnitus patients compared to control subjects in FDG-PET, analysed with SPM5. Our estimation is that this cortical hyperactivity is localised in the primary auditory cortex and the associative auditory cortex, although other regions might display some hyperactivity as well	—

Countries

Netherlands

Outcome results