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Thorax injury in relation with systemic neutrophil activation

Thorax injury in relation with systemic neutrophil activation - THOR study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON31401
Enrollment
30
Registered
2007-12-04
Start date
2008-02-29
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trauma, immuunsysteem en longaandoeningen Acute respiratory distress syndrome ARDS Pulmonary failure

Interventions

None listed

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Thorax trauma (AIS > 2) Age 18 - 70

Exclusion criteria

Exclusion criteria: Additional trauma (AIS > 2) Immunological compromized (corticosteroids, chemotherapy)

Design outcomes

Primary

MeasureTime frame
Primary parameter: Activation of neutrophils (receptor profiles) and local injury Primary endpoint: Development of ARDS

Secondary

MeasureTime frame
Secondary endpoints: Trauma severity (HTTSS / NISS / Blood gas on admission) Difference between penetrating and blunt trauma

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)