investigation of the relation between trombo-embolic events and microparticles in essential thrombocythemia and polycythemia vera patients

investigation of the relation between trombo-embolic events and microparticles in essential thrombocythemia and polycythemia vera patients - Microparticles in ET&PV patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31395

Enrollment

Registered

2007-10-23

Start date

2007-08-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

blood disease myeloproliferative disorders

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients who meet WHO criteria for PV and ET

Exclusion criteria

Exclusion criteria: we have no exclusion criteria

Design outcomes

Primary

Measure	Time frame
Number of Annexin V positive microparticles in patients and controls as well as the expression of different antibodies in this Annexin V positive. Endogene trombine potential of patients and controls. We will describe the relationship of these microparticles with medication, jak2V17 mutation and history of thrombo-embolic events in patients and controls	—

Secondary

Measure	Time frame
We will describe the relation between these microparticles and Von Willebrand factor antigen and propeptide, E-selectin, thrombocytes, age and gender.	—

Countries

Netherlands

Outcome results