Circadian rhythm of erythropoietin and melatonin in patients with various degrees of renal insufficiency, Part one

Circadian rhythm of erythropoietin and melatonin in patients with various degrees of renal insufficiency, Part one - Circadian Rhythm of Erythropoietin and Melatonin in renal disease /CREAM 1

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31373

Enrollment

Registered

2007-05-11

Start date

2007-08-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

biological rhythm circadian processes

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: o Patient with various degrees of renal insufficiency, creatinin clearance: minimum 10 ml/min (measured with MDRD), admitted in our hospital o Informed Consent o Man/Women between 18 and 85 years o Understanding and knowledge of the dutch language

Exclusion criteria

Exclusion criteria: o Instable angina pectoris, heart failure NYHA class IV o Therapy with erythropoetin, melatonin or/and hypnotics o Acute renal failure or rapidly progressive glomerulonephritis o Bleeding or haemolysis as a cause of anaemia o Deficiency of iron, folate and/or vitamin B12 o Presence of chronic inflammatory disease or clinically significant infection o Haemoglobinopathies o Alcohol and/or drug abuse o Enrolment in another study o Any kind of disorder that compromises the ability of the subject to give written informed consent and/or to comply with study procedures

Design outcomes

Primary

Measure	Time frame
Analysis of the existence of a circadian rhythm in patients with a normal renal function and in patients with variable degrees of renal insufficiency	—

Countries

Netherlands

Outcome results