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Investigation of the somatotopic organization of the subthalamic nucleus in Parkinson's patients with deep brain stimulation; movement measurements on Parkinson*s Disease patients for different deep brain stimulation settings.

Investigation of the somatotopic organization of the subthalamic nucleus in Parkinson's patients with deep brain stimulation; movement measurements on Parkinson*s Disease patients for different deep brain stimulation settings. - Somatotopic organization of the subthalamic nucleus

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON31328
Enrollment
15
Registered
2007-09-20
Start date
2007-10-01
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's Disease

Interventions

The intervention of this research project is based on influencing the stimulator. The stimulator is adjusted to 4 different settings, of which 3 are different than the original setting of the stimul

Sponsors

Medisch Spectrum Twente
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patient suffers from Parkinson's disease Patient has received bilateral DBS in the STN Patient underwent surgery at least three month ago Patient experiences a good clinical result from DBS Patient has no major fluctuations in symptoms due to medication Patient is in good physical condition Patient responds within 5 minutes to changes in the stimulator settings

Exclusion criteria

Exclusion criteria: Patient cannot fully cooperate with the experiments Patient suffers from dementia Patient suffers from severe dyskinesia/akinesia

Design outcomes

Primary

MeasureTime frame
The study is designed to measure tremor, bradykinesia/akinesia and speech dificiencies in Parkinson's disease. These factors can than be related to the position of the electrode which is determined from preoperative MRI scans or post-operative CT scans.

Secondary

MeasureTime frame
n.a.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)