C-reactive protein assisted prescribing for respiratory tract infections to stimulate Antibiotic stewardship; a randomised controlled trial in general practice

C-reactive protein assisted prescribing for respiratory tract infections to stimulate Antibiotic stewardship; a randomised controlled trial in general practice - CAPRESA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON31304

Enrollment

200

Registered

2007-10-22

Start date

2007-11-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

respiratory tract infections

Interventions

PoC CRP assisted antibiotic prescribing including delayed prescribing compared to usual care

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: LRTI: First consultation of current episode of acute cough (duration

Exclusion criteria

Exclusion criteria: Patients who require immediate admission to hospital Patients who have no understanding of written and/or Dutch language Patients who previously participated in the study Patients who currently use antibiotic or have taken an antibiotic in the past 2 weeks Patients who have been hospitalized in the past 2 weeks Severely immuno-compromised patients

Design outcomes

Primary

Measure	Time frame
Prescribing rates at index consultation (day 0), defined as immediate, delayed or no antibiotics	—

Secondary

Measure	Time frame
- Total antibiotic exposure over a period of 28 days, defined as the number of patients receiving immediate antibiotics or filling a delayed prescription for antibiotics within 28 days of index consultation (day 0) - Clinical recovery - Patient satisfaction and enablement - Reconsultation within 28 days - Evaluation of GPs' estimation of CRP value based on usual diagnostic work-up (medical history and physical examination) compared to actual CRP test result. - CRP value on day 0 and day 7 in relation to perceived degree of illness (VAS, Visual Analogue Scale).	—

Measure

Time frame

- Total antibiotic exposure over a period of 28 days, defined as the number of patients receiving immediate antibiotics or filling a delayed prescription for antibiotics within 28 days of index consultation (day 0) - Clinical recovery - Patient satisfaction and enablement - Reconsultation within 28 days - Evaluation of GPs' estimation of CRP value based on usual diagnostic work-up (medical history and physical examination) compared to actual CRP test result. - CRP value on day 0 and day 7 in relation to perceived degree of illness (VAS, Visual Analogue Scale).

—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)