Regulation of Apoptosis in Cultured Nasal Airway Epithelial Cells of Children

Regulation of Apoptosis in Cultured Nasal Airway Epithelial Cells of Children - n.a.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31297

Enrollment

Registered

2007-04-18

Start date

2007-04-15

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

programmed celdeath

Interventions

None listed

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: age 2-24 months patient of: Emma Children's Hospital (outpatient clinic / ward)

Exclusion criteria

Exclusion criteria: History of pulmonary disorder No permission of caretakers

Design outcomes

Primary

Measure	Time frame
Evidence for apoptosis: caspase-3 activity, annexin-V binding and morphological studies. Apoptotic pathways: RNA of the Bcl-2 and IAP family of pro- and anti-apoptotic factors, RNA and protein analysis of Fas/FasL and caspase-8 and -9 activity.	—

Secondary

Measure	Time frame
n.a.	—

Countries

Netherlands

Outcome results