Validation of 3.0 Tesla 1H-MR Spectroscopy for assessment of liver steatosis in patients with non-alcoholic fatty liver disease and chronically infected hepatitis C

Validation of 3.0 Tesla 1H-MR Spectroscopy for assessment of liver steatosis in patients with non-alcoholic fatty liver disease and chronically infected hepatitis C - Validation of 3.0 Tesla 1H-MR Spectroscopy for liver steatosis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31271

Enrollment

Registered

2007-09-25

Start date

2007-08-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fatty liver hepatitis C jaundice liversteatosis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients over 18 years of age Patients with signs of non-alcoholic fatty liver disease and who require liver biopsy for steatosis assessment Patients chronically infected with hepatitis C and who require liver biopsy

Exclusion criteria

Exclusion criteria: Patients under 18 years of age Patients who are pregnant Hepatitis C patients with HOMA-IR score 40 grams per week Patients who are claustrophobic Patients who have magnetic or radiofrequency sensitive implants Patients with extreme obesity (maximum weight limit MRI scanner 140kg)

Design outcomes

Primary

Measure	Time frame
Validation and quantification of hepatic steatosis with 3.0 Tesla 1H-MRS in patients with non-alcoholic fatty liver disease or chronically infected hepatitis C and correlation with histological analysis of the liver biopsy and clinical parameters	—

Secondary

Measure	Time frame
nvt	—

Countries

Netherlands

Outcome results