Prolonged repetitive nerve stimulation (RNS) in myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS): quantitative and relevant.

Prolonged repetitive nerve stimulation (RNS) in myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS): quantitative and relevant. - Prolonged RNS in myasthenia

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31264

Enrollment

Registered

2007-10-11

Start date

2007-09-15

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myasthenia MG LEMS

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: over 18 years old MG: clinical signs and symptoms of MG, positive for anti-AChR antibodies and characteristic RNS EMG abnormalities (decrement over 10%) or abnormal Single Fibre EMG. LEMS: clinical signs and symptoms of LEMS, positive for anti-VGCC antibodies and characteristic RNS EMG abnormalities (decrement over 10% and increment over 60%) or abnormal Single Fibre EMG.

Exclusion criteria

Exclusion criteria: anticoagulant drugs muscle and nerve diseases or diseases predisposing to nerve or muscled isease, for example diabetes mellitus

Design outcomes

Primary

Measure	Time frame
CMAP-amplitude and change of amplitude after prolonged stimulating and recording. Is hte pattern different between controls itselves and between controls and patients?	—

Secondary

Measure	Time frame
Is the technique painless indeed?	—

Countries

Netherlands

Outcome results