the role of subcutaneous and visceral fat tissue in the mechanism of obesity induced insulin resistance

the role of subcutaneous and visceral fat tissue in the mechanism of obesity induced insulin resistance - insulin resistance mechanisms in subcutaneous and visceral fat tissue

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31248

Enrollment

250

Registered

2007-08-20

Start date

2007-10-08

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

insulin resistance and diabetes

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: healthy women between 18-75 years of age undergoing abdominal surgery for gynaecological diseases

Exclusion criteria

Exclusion criteria: fever dissiminated gynaecological oncolocgical disease

Design outcomes

Primary

Measure	Time frame
The comparison of subcutaneous and visceral tissue in the following subanalyses: Quantitative proteomics for the comparison of different secretomes (n=30) Interactions of macrophages and adipocytes in human fat tissue (n=60) Interactions between bowel hormones and short chain fatty acids and fat tissue (n=60) production of exosomes by fat tissue (n=50) validation of the proteins found in relation with BMI (n=50) correlation of the scretomes with serum levels	—

Measure

Time frame

The comparison of subcutaneous and visceral tissue in the following subanalyses: Quantitative proteomics for the comparison of different secretomes (n=30) Interactions of macrophages and adipocytes in human fat tissue (n=60) Interactions between bowel hormones and short chain fatty acids and fat tissue (n=60) production of exosomes by fat tissue (n=50) validation of the proteins found in relation with BMI (n=50) correlation of the scretomes with serum levels

—

Secondary

Measure	Time frame
see above	—

Countries

Netherlands

Outcome results