Mannose-binding Lectin Deficiency and the Risk of Infectious Complications in Trauma Patients.

Mannose-binding Lectin Deficiency and the Risk of Infectious Complications in Trauma Patients. - MBL Deficiency in Trauma

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31242

Enrollment

100

Registered

2008-05-27

Start date

2007-06-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

(Multiple) organ failure Infections

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Trauma patients admitted to the shock room of the emergency department of the Academic Medical Center, Amsterdam. These patients either meet the criteria of high energy trauma, or are otherwise suspected to have potentially life threatening injuries.

Exclusion criteria

Exclusion criteria: Patients younger then 18 years old.

Design outcomes

Primary

Measure	Time frame
Plasma concentration levels of MBL in trauma patients.	—

Secondary

Measure	Time frame
Development of infectious complications and death within the first 30 days after trauma in relationship to baseline and follow-up plasma levels of MBL. - ISS, age, gender, region of injury, mortality. - pneumonia, ARDS, SIRS, MOF, sepsis, wound infection, wound dehiscence, urinary tract infection, intra-abdominal abscess.	—

Countries

Netherlands

Outcome results