A pilot study investigating the possible relation between inter-subject variation in parameters of whole saliva and differences in susceptibility to erosion

A pilot study investigating the possible relation between inter-subject variation in parameters of whole saliva and differences in susceptibility to erosion - The relation between erosion and saliva characteristics

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31241

Enrollment

Registered

2007-11-13

Start date

2007-11-28

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tandweefsel dental erosion wear

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adults with an ASA score of 1 with a rehabilitated dentition

Exclusion criteria

Exclusion criteria: An ASA score of 2 or higher, severe periodontal disease (Dutch periodontal screening index, DPSI > 2) and an unrehabilitated dentition

Design outcomes

Primary

Measure	Time frame
From all participants the saliva composition (proteins and minerals) and saliva characteristics (pH, buffer capacity, viscosity) will be determined. Also the loss of hydroxyapatite after an erosive challenge will be measured. The correlation between different saliva parameters and the susceptibility to erosive wear will be calculated. Depending on this correlation and the spread of the data a power analysis will be performed and the sample size will be determined.	—

Measure

Time frame

From all participants the saliva composition (proteins and minerals) and saliva characteristics (pH, buffer capacity, viscosity) will be determined. Also the loss of hydroxyapatite after an erosive challenge will be measured. The correlation between different saliva parameters and the susceptibility to erosive wear will be calculated. Depending on this correlation and the spread of the data a power analysis will be performed and the sample size will be determined.

—

Secondary

Measure	Time frame
nvt	—

Countries

Netherlands

Outcome results