groeistoornissen growth retardatrion short-stature
Conditions
Interventions
All children undergo an arginine-growth hormone stimulation test and one other
test (L-dopa, sleeping or chondiline), because of suspected growth retardation
based on one of the anthropametric crite
Sponsors
Wageningen Center for Food Sciences
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: Eligibility for GHST's is based on one or more of the anthropometric criteria characterizing GH deficient patients: * Height less than -2,5 SDS * Deviation from target height more than 1.3 SDS * Deviation of growth more than -0.25 SDS.
Exclusion criteria
Exclusion criteria: Children will be excluded if other reasons than those related to GH for growth retardation were present. Because it is known that girls with Turner syndrome show a growth response to GH therapy, they will be included in the tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A difference in reliability in the diagnose of GH-deficiency with the GHST*s and the protein test, using TBW-test. TBW-test is the evaluation test in this study to compare the predicting power of the diagnostic tests. TBW-test is used to evaluate GH-therapy after 6 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| - | — |
Countries
Netherlands
Outcome results
None listed