Muscle Sympathetic Nerve Activity and Cardiovascular Organ Damage in Patients with Chronic Kidney Disease and Hypertension

Muscle Sympathetic Nerve Activity and Cardiovascular Organ Damage in Patients with Chronic Kidney Disease and Hypertension - Sympathetic activity and cardiovascular organ damage

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31233

Enrollment

Registered

2007-10-23

Start date

2007-12-21

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertensie Chronic kidney disease Chronic Renal Disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with hypertension (i.e. using antihypertensive drugs and/or blood pressure >145/90mmHg when off medication) with stable chronic kidney disease

Exclusion criteria

Exclusion criteria: Patients with clinically manifested cadiac history

Design outcomes

Primary

Measure	Time frame
-Primary endpoint: Left ventricular (LV) mass; -Primary expected outcome: a proportional relation between MSNA and LV mass	—

Secondary

Measure	Time frame
-Secondary endpoints: o Glomerular filtration rate (GFR); o Ejection Fraction -Secondary expected outcome: o Decrease in GFR as compared to baseline o Decrease in Ejection Fraction as compared to normal population	—

Countries

Netherlands

Outcome results