Genetic aspects of Barrett Esophagus

Genetic aspects of Barrett Esophagus - GENBAR

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31201

Enrollment

1500

Registered

2007-07-12

Start date

2007-05-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Barrett Esophagus

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients: - Age >= 18 years - Informed consent - Participating in the CYBAR study ( histological confirmation of diagnosis of BE);Family members: - Age >= 18 years - Informed consent

Exclusion criteria

Exclusion criteria: - Unable to fill out questionnaire

Design outcomes

Primary

Measure	Time frame
•Familial incidence of GERD, BE and EAC in first en second degree relatives of patients with BE in the Netherlands.	—

Secondary

Measure	Time frame
•Gene-environment interactions on familial susceptibility to GERD and BE •Incidence of EAC in family members of patients with GERD and BE. •Reported polymorphisms in BE are predictive for developing BE in relatives of patients with this disorder.	—

Countries

Netherlands

Outcome results