Anxiety disorder post traumatic stress disorder
Conditions
Interventions
None listed
Sponsors
Universiteit van Amsterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: All subjects have experienced a work-related trauma. The main inclusion criteria for the experimental group is to meet the DSM IV criteria for PTSD as a consequence of a work related trauma.
Exclusion criteria
Exclusion criteria: The main exclusion criteria all subjects are; severe concentration problems, visual problems, hearing problems, pregancy, cardiovascular complaints and epilepsy. ;Exclusion criteria for the experimental group is severe comorbidity and PTSD as a consequence of complex trauma. Exclusion criteria of the control group are any DSM IV diagnosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. *Startle* respons is measured by exposure to the *startle probe*. Door middel van deze respons wordt de mate van angst en uiteindelijk de mate van inhibitie gemeten. De *startle probe* (akoestische stimulus) wordt binauraal door een koptelefoon geleverd. De *startle probe* bestaat uit een witte ruis (alle frequenties omvattende) geluidsstimulus met een geluidsdrukniveau van 104-dbA en een duur van 40 msec. 2. Cognitive expectancy/contingency awareness: the online US expectancy is measured on a 11- point scale from certainly no electrical pulse to uncertain to *certain a elektric pulse'. After every stimulus presentation the online expectancy is registered. 3. Propositional knowledge: after the computertask is finished the questionnaire about the obtained knowledge about the stimuli are answered. | — |
Secondary
| Measure | Time frame |
|---|---|
| Using the human fear conditioning paradigm it is demonstrated that the effects of extinction are largely confined to the context in which the extinction procedure took place (Vansteenwegen, Hermans, Vervliet et al., 2005). From the clinical viewpoint, it is suggested that changes in the constellation of the therapy context contribute to the sometimes reported Return of fear (Rachman, 1989) following successful therapy completion (see also Bouton, 2002) Bouton and colleagues (e.g. Bouton & Nelson) For these reasons, the effects of context on (transfer of) inhibition performance will be tested. It will be hypothesized that patients with PTSD will show less transfer of inhibition to another test context than controls. In other words, patients regard the safety cue in another context as less inhibitory. | — |
Countries
Netherlands
Outcome results
None listed