Cerebral perfusion, measured by Arterial Spin Labeling (ASL) perfusion MRI, in relation to outcome in children and young adults with ischaemic stroke

Cerebral perfusion, measured by Arterial Spin Labeling (ASL) perfusion MRI, in relation to outcome in children and young adults with ischaemic stroke - Brain perfusion in relation to outcome in young stroke patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31120

Enrollment

Registered

2008-03-11

Start date

2008-04-29

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ischaemic stroke

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: For patients in the retrospective cohort: - Children at the age of 7 years - 18 years and adults between 18 and 50 years of age - Patients can undergo MR imaging on the 3 Tesla MR scanner without the necessity for anaesthesia (children > 6 years of age) - Patients treated in the UMC Utrecht for arterial ischaemic stroke in the anterior cerebral circulation between January 2000 and August 2007 - Proven non-atherosclerotic arteriopathy at vascular imaging

Exclusion criteria

Exclusion criteria: Contra-indications for MRI (claustrophobia; pacemaker or automatic defibrillator; some mechanical heart valves; swan-ganz catheter; some aneurysm clips; gastrointestinal clips; cochlear implant; metal object in eye; dental prosthesis with magnetic attachment; hip prosthesis and metal hipnails of more than 50 cm; hydrocephalus- or insulinpump; uncovered skin; medicine patch; piercing)

Design outcomes

Primary

Measure	Time frame
Primary outcome measure: functional outcome, defined as good or poor. Standardized outcome measures for stroke will be used (Paediatic Stroke Outcome Measure (PSOM)), modified Rankin Scale (mRS) and Quality of Life outcome scales).	—

Secondary

Measure	Time frame
Secondary outcome measure: recurrent stroke during follow-up	—

Countries

Netherlands

Outcome results