Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) at different magnetic field strengths in healthy volunteers

Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) at different magnetic field strengths in healthy volunteers - DWIBS at different magnetic field strengths

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31117

Enrollment

Registered

2007-08-21

Start date

2007-11-14

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Het betreft onderzoek naar beeldkwaliteit en normale lymfeklieren bij gezonde vrijwilligers lymph node cancer Malignant lymphomas

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - male or female volunteers - age: 18 years and older - the participant must willingly give written informed consent prior to the start of the study

Exclusion criteria

Exclusion criteria: - volunteers who underwent surgery in the past - volunteers who had a malignancy in the past - volunteers who have been or are suffering from a chronical inflammation or infection - volunteers using medication at present - volunteers who suffered from a transient infection within the past two months - volunteers with symptoms possibly indicating an active inflammation or infection (e.g. fever, chills, night sweats, malaise, weight loss, fatigue, rhinorrhoe, coughing, throat ache, nausea, vomiting, diarrhea, etc.) - volunteers with a general contraindication for MRI (including cardiovascular pacemakers, claustrofobia) -volunteers who don't want to be informed about incidentally discovered lesions -employees of the Department of Radiology of the UMC Utrecht

Design outcomes

Primary

Measure	Time frame
1 a) Image quality of DWIBS obtained at different magnetic field strengths and with different fat-suppression techniques: average apparent contrast-to-noise ratio's with corresponding standard deviations of DWIBS-images obtained at 1.0 T, 1.5 T, and 3.0 T and with different fat-suppression techniques (STIR versus SPIR/SPAIR) will be compared 1 b) Image quality of three respiration techniques in DWIBS of the liver: image quality on a scale of 1 (poor) to 5 (very good) of breathhold, "respiratory triggered, and free breathing scanning will be compared 2) A mean ADC with SD will be calculated for non-malignant (normal) lymph nodes.	—

Measure

Time frame

1 a) Image quality of DWIBS obtained at different magnetic field strengths and with different fat-suppression techniques: average apparent contrast-to-noise ratio's with corresponding standard deviations of DWIBS-images obtained at 1.0 T, 1.5 T, and 3.0 T and with different fat-suppression techniques (STIR versus SPIR/SPAIR) will be compared 1 b) Image quality of three respiration techniques in DWIBS of the liver: image quality on a scale of 1 (poor) to 5 (very good) of breathhold, "respiratory triggered, and free breathing scanning will be compared 2) A mean ADC with SD will be calculated for non-malignant (normal) lymph nodes.

—

Secondary

Measure	Time frame
The number of non-analyzable images will be registered.	—

Countries

Netherlands

Outcome results