CArdiac magnetic resonance perfusioN imaging for SELection of patients for additional invasive evaluation after CT coronary angiography (CANSEL)

CArdiac magnetic resonance perfusioN imaging for SELection of patients for additional invasive evaluation after CT coronary angiography (CANSEL) - CANSEL

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31103

Enrollment

Registered

2007-08-06

Start date

2007-08-20

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary atherosclerosis MRI

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Suspected obstructive CAD on CT-CA 2. Planned invasive coronary angiography

Exclusion criteria

Exclusion criteria: 1. Previous myocardial infarction 2. Previous percutaneous coronary intervention or coronary artery bypass grafting 3. Contraindications for MRI 4. Possible pregnancy and/or breast feeding 5. Inability to breath hold for up to 15 seconds 6. Inability to give reliable informed consent 7. Known claustrophobia 8. Unstable coronary artery disease 9. Known allergy to contrast material 10. Renal insufficiency 11. COPD.

Design outcomes

Primary

Measure	Time frame
We expect a high sensitivity and specificity for first pass magnetic resonance imaging to detect a significant coronary artery stenosis as determined by FFR. Determination optimal cut of value. There is no benefit for the individual patient. In the future in patients with coronary stenosis identified by CT-CA, myocardial perfusion MRI will predict who may benefit from coronary revascularisation. Furthermore the combination of CT-CA, and myocardial perfusion study using magnetic resonance will also predict who do not have a coronary stenosis and therefore do not need ICA.	—

Measure

Time frame

We expect a high sensitivity and specificity for first pass magnetic resonance imaging to detect a significant coronary artery stenosis as determined by FFR. Determination optimal cut of value. There is no benefit for the individual patient. In the future in patients with coronary stenosis identified by CT-CA, myocardial perfusion MRI will predict who may benefit from coronary revascularisation. Furthermore the combination of CT-CA, and myocardial perfusion study using magnetic resonance will also predict who do not have a coronary stenosis and therefore do not need ICA.

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Countries

Netherlands

Outcome results