psychotic proneness schizotypy
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: psychotic proneness, depression proneness
Exclusion criteria
Exclusion criteria: Subjects with history of psychiatric or relevant neurologic disease, for which they have been treated will be excluded from the study. Subjects who have not been treated for or diagnosed with a psychiatric disorder, but for who the screening questions of the CIDI give an indication of having a psychiatric disorder, will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In the present study, by using fMRI, we would like to investigate the activation of distinct brain areas engaged during self-evaluation, emotion regulation, self-perspective inhibition, affective and cognitive mentalizing, and reality monitoring, all being crucial cognitive-emotional processes involved in insight. fMRI has the best spatial resolution amongst the other non-invasive techniques which allow one to have the closest look at the neuronal activity available with imaging. Furthermore, current studies which have been investigating cognitive processes related to self-awareness and emotion regulation are mostly behavioral. Additionally, the few available studies on the use of fMRI paradigms has been indeed promising toward an effective delineation of the neural correlates subserving these functions by this technique. In light of this, the proposed study would be an innovative research that, besides elucidating the cognitive and neural basis of subclinical psychotic symptoms, will also inform our future studies of self-processing in relation to poor insight (illness awareness) in psychosis. | — |
Countries
Netherlands
Outcome results
None listed