atherosclerosis coronary disease
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: -Patients suspected for coronary artery disease or with an acute coronary syndrome and therefore have to undergo a diagnostic coronary angiogram. -A written informed consent obtained. -Renal functions will be estimated by calculating the kreatinine clearance and glomerular filtration rate (GFR), according to the Cockroff-Gault formula before the procedure and where possible 24 hours after the procedure. The astimated kreatinine clearance must be > 90ml/min/1.73m2.
Exclusion criteria
Exclusion criteria: - age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Qualitative and quantitative scoring for coronary stenosis (severity and numbers), coronary anatomy (left- or right system dominance; separate ostia LAD/CX; other coronary anomalies), TIMI-flow, thrombus, dissection and calcification. Qualitative stenosis scoring wil take place in the conventional projectings of the RCA and LCA and in the rotation projections of the RCA and LCA. The quantitative stenosis scooring will be performed with QCA software (quantitative coronary angiogram) on the conventional projections, the rotation images and with the Allura system on the created 3D coronairy model. -After the diagnostic coronary procedure, the obtained projections of the conventional projection, the rotation projection and the 3D reconstruction model are independently scored by 2 interventional cardiologists. -Patient characteristics and the obtained data from the coronary projections are analyzed in a database. -. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Comparison will take place fore possible variations in used x-ray contrast fluid and radiation dose at the different projection techniques. | — |
Countries
Netherlands
Outcome results
None listed