neonatal hypoglycemia
Conditions
Interventions
Intervention: In the intensive treatment arm the aim is to increase the glucose
concentration above 2.5 mmol/l within 3 hours by increasing the carbohydrate
intake by oral nutrition and/or intraveno
Sponsors
Academisch Medisch Centrum
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: Infants with one of the four major risk factors for neonatal hypoglycemia, who are routinely screened for neonatal hypoglycemia in current clinical practice: 1. Small-for-gestational-age infants (SGA, birth-weight-for-gestational-age P90); 3. Near-term infants 35 0/7 to 36 6/7 weeks gestational age with a birth weight >2000 gram; 4. Infants of diabetic mothers (IDM). Birth-weight-for-gestational-age is defined according to the Kloosterman growth charts.
Exclusion criteria
Exclusion criteria: Infants with serious co-morbidity will be excluded, because their co-morbidity can also affect neurodevelopment: 1. Very preterm infants (
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome is neurodevelopment at 18 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are costs for medical treatment and hospital admission until 18 months of age. | — |
Countries
Netherlands
Outcome results
None listed