Restoration of cardiac function and regional pulmonary blood flow in chronic thromboembolic pulmonary hypertension after pulmonary endarterectomy assessed during exercise by magnetic resonance imaging

Restoration of cardiac function and regional pulmonary blood flow in chronic thromboembolic pulmonary hypertension after pulmonary endarterectomy assessed during exercise by magnetic resonance imaging - Restoration of cardiac function and regional blood flow after PEA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30973

Enrollment

Registered

2007-04-18

Start date

2007-04-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic pulmonary embolism chronic thromboembolic pulmonary hypertension

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Part one study: Operable CTEPH Part two study: Patients after PEA with near-normalized pulmonary artery pressure

Exclusion criteria

Exclusion criteria: Renal insufficiency (creatinin >115 umol/l) Part one study: generally accepted contraindications for MRI Part two study: also: residual pulmonary hypertension (mean PAP>30 mmHg)

Design outcomes

Primary

Measure	Time frame
1) Level of restoration of right ventricle stroke volume response during exercise 2) Level of restoration of regional blood flow after PEA	—

Secondary

Measure	Time frame
1) Relationship between the level of restoration of cardiac function and the level of restoration of regional blood flow 2) Relationship between the level of restoration of cardiac function and the directly postoperative observed hemodynamic improvement.	—

Countries

Netherlands

Outcome results