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Affective startle modulation in personality disordered offenders

Affective startle modulation in personality disordered offenders - The startle response in personality disordered offenders

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON30963
Enrollment
120
Registered
2007-10-11
Start date
2008-02-01
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psychopathy

Interventions

None listed

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Psychopathy (pcl-r score >=26) Antisocial personality disorder according to the DSM-IV criteria

Exclusion criteria

Exclusion criteria: Specific exclusion criteria for patients: psychotic patients. Exclusion criteria for both patients and controls: colour blindness, deafness or hard of hearing, neurological, cardiovascular, and respiratory diseases. Subjects will also be excluded when they cannot understand the Dutch language sufficiently to understand the purposes and implications of the experiment.

Design outcomes

Primary

MeasureTime frame
Emotional functioning of psychopaths and ASPD-patients with a low PCL-R score will be studied by means of psychophysiological (Heart rate, blood pressure, skin conductance, breathing rate and eyeblink and post-auricular EMG), HPA axis (Salivary cortisol levels) and psychodiagnostic and risk-assessment instruments to investigate whether there are subgroups of antisocial offenders, who can be differentiated on the basis of affective response patterns.

Secondary

MeasureTime frame
Type and dose of medication Duration of treatment with medication Criminological anamnesis Type and number of convictions Age of first conviction

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)