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Chronic inflammation and development of cancer in the esophagus

Chronic inflammation and development of cancer in the esophagus - Inflammation and cancer in the esophagus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON30962
Enrollment
80
Registered
2007-10-23
Start date
2007-12-05
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic reflux disease heart burn

Interventions

None listed

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - >= 18 years old - written informed consent - upper or lower gastrointestinal tract endoscopy for diagnosis or follow-up of pre-malignant disorder of the gastrointestinal tract

Exclusion criteria

Exclusion criteria: - pregnancy - esophagectomy, gastrectomy - total proctocolectomy

Design outcomes

Primary

MeasureTime frame
The main study parameter is a significant difference in the number and type of DCs in the esophagus of patients with chronic gastro esophageal reflux disease and BE.

Secondary

MeasureTime frame
- To determine DC populations in blood - To relate the above-mentioned findings of DC to other pre-malignant gastrointestinal disorders, i.e., Crohn*s disease and ulcerative colitis.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)