caries caries tooth decay
Conditions
Interventions
Participants with caries on the buccal surfaces upon removal of the fixed
appliances will be put on a rigid oral hygiene program. One-half of subjects
will also receive a a paste containing Casein P
Sponsors
Academisch centrum voor tandheelkunde
Eligibility
Age
12 Years to 17 Years
Inclusion criteria
Inclusion criteria: Subject is enrolled as patient at the orthodontic clinic of ACTA, and receives orthodontic treatment with fixed appliances and is scheduled for debracketing. Subject is between 12 and 18 years old at the start of the study. Subject, and also a parent or guardian, have signed the informed consent form prior to the start of the study. Subjects have at least two detectable caries lesions on their buccal surfaces immediately after debracketing.
Exclusion criteria
Exclusion criteria: Subject is younger than 12 years old or older than 18 years old. Subject is mentally not capable to understand and follow instructions. Subject suffers from a systemic illness. Subject is milk protein intolerant, because this may provoke an allergic reaction to the CPP-ACP paste. Subject has caries lesions that need restorative care.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of Caries lesions, change in lesion extent expressed by their fluorescence loss and lesion area over a one-year study period. | — |
Secondary
| Measure | Time frame |
|---|---|
| Plaque composition and acidogenicity | — |
Countries
Netherlands
Outcome results
None listed