Influence of Mannose-Binding Lectin Polymorphisms on Infectious Complications in Trauma Patients

Influence of Mannose-Binding Lectin Polymorphisms on Infectious Complications in Trauma Patients - MBL Polymorphisms in Trauma Patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30944

Enrollment

450

Registered

2007-11-12

Start date

2007-12-01

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MBL-deficiency suboptimal immune status

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Trauma patients with an ISS of 16 or higher Age between 18 and 70 years Compos mentis Informed consent

Exclusion criteria

Exclusion criteria: ISS70 years Death within 24 hours after the trauma No informed consent Patients with a known immune disorder Use of immunosuppressive drugs

Design outcomes

Primary

Measure	Time frame
Bacteremia (BSI) Pneumonia Systemic Inflammatory Response Syndrome (SIRS) Sepsis Septic shock	—

Secondary

Measure	Time frame
Death within 3 months Surgical site infection Osteitis after osteosynthesis of fractures	—

Countries

Netherlands

Outcome results