Study of the effects of cytotoxic chemotherapy on oral microcirculation in patients with acute myeloid leukemia (AML)

Study of the effects of cytotoxic chemotherapy on oral microcirculation in patients with acute myeloid leukemia (AML) - Effects of cytotoxic chemotherapy on oral microcirculation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30919

Enrollment

Registered

2007-07-12

Start date

2007-02-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bloed doorstroming in de microvaten acute myeloid leukemia leukemia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. * Patients receiving chemotherapeutic treatment in the Department of Clinical Hematology in the Academic Medical Center (AMC) 2. * Patients with acute myeloid leukemia (AML) 3. * Informed consent from each participating patient 4. * Patients older than 18 years

Exclusion criteria

Exclusion criteria: 1. * Severe cardiac and/or pulmonary pathologies 2. * Severe renal function disorders 3. * Hypertension 4. * Patients using anticoagulants or corticosteroids (local or systemic) 5. * Patients with other cancers other than acute myeloid leukemia (AML) 6. * Patients that did not sign an informed consent 7. * Patients younger than 18 years

Design outcomes

Primary

Measure	Time frame
Noninvasive measurements: Sidestream Dark-Field (SDF) Imaging * microcirculation quantification Invasive measurements: Blood sample * VEGF, bFGF, and MMPs	—

Secondary

Measure	Time frame
n.v.t.	—

Countries

Netherlands

Outcome results