mediastinitis mediastinitis sternal infection
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: All patients diagnosed with postoperative mediastinitis receiving one of the following treatments: - reconstruction with a vascularised soft tissue flap (omentum and/or pectoral muscle flap), followed by closure with a split-skin graft - closed irrigation system - open wound treatment - VAC-therapy, followed by sternal closure and a reconstruction with a partial pectoral muscle flap and immediate closure of the soft tissue defect
Exclusion criteria
Exclusion criteria: - all patients diagnosed with postoperative mediastinitis not receiving one of the above treatments (e.g. VAC-therapy only);- patients diagnosed with postoperative mediastinitis who died before receiving treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical outcome and survival of the two groups: conventional versus closed sternum treatment. Outcome and survival will be determined by mortality rate, sternal closure, pain or loss of function, ability to perform same preoperative activities (work/hobby), clinical data. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical outcome and survival of the subgroups of conventional treatment: omentum flap reconstruction, pectoral flap reconstruction, irrigation system and open wound treatment. Other secondary parameters will be occurrence of mediastinitis to determine incidence and possible risk factors for mediastinitis, such as diabetes, BMI>30, COPD and number of sternal wires. | — |
Countries
Netherlands
Outcome results
None listed