Combined electromyography-functional MRI in patients with tremor for improvement of targeting in stereotactic surgery

Combined electromyography-functional MRI in patients with tremor for improvement of targeting in stereotactic surgery - EMG-fMRI for tremor in stereotactic surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30841

Enrollment

Registered

2007-10-09

Start date

2007-11-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

shaking trembling tremor

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Previous thalamotomy for the treatment of tremor or inclusion in the waiting list for DBS;Presence of tremor in at least one arm ;Age above 18 years

Exclusion criteria

Exclusion criteria: MR-incompatible implanted metal bodies, including stereotactic implant for Deep Brain Stimulation.;Other contraindications for MR (Claustrophobia, obesity, etc.);Previous brain surgery other than thalamotomy ;Use of medicines/drugs that could influence the performance during the tasks (such as anti-epileptic drugs, neurodepressants, etc.);Pregnancy or suspected pregnancy;Incapability to give informed consent

Design outcomes

Primary

Measure	Time frame
We will evaluate the predictive value of EMG-fMRI by correlating the overlap of the area defined by EMG-fMRI with the surgical area, and with clinical outcome of surgery. Effectiveness of treatment (thalamotomy or DBS) will be assessed according to the change in the score of specific clinical scales (UPDRS and TRS).	—

Countries

Netherlands

Outcome results