DEVELOPMENT, IMAGING AND QUANTIFICATION OF VULNERABILITY IN HUMAN CAROTID PLAQUES.

DEVELOPMENT, IMAGING AND QUANTIFICATION OF VULNERABILITY IN HUMAN CAROTID PLAQUES. - plaque vulnerability

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30835

Enrollment

Registered

2007-07-18

Start date

2007-05-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unstable plaque vulnerable plaque

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: asymptomatic stenosis of the internal carotid artery, stenosis >80% symptomatic stenosis of the internal carotid artery, stenosis >70%

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
Endpoints will be: - the find of biomarkers where symptomatic patients are compared with asymptomatic patients - the find of certain proteins at proteomics (or hedgehog signals) which can be correlated to both the presence of the plaque, and (preoperative) symptoms of the patient. - showing a detectable signal at fluorescence, a relation will be sought between the intensity of the signal and the vulnerability of the plaque (related to previously detected biomarkers and patient symptoms).	—

Measure

Time frame

Endpoints will be: - the find of biomarkers where symptomatic patients are compared with asymptomatic patients - the find of certain proteins at proteomics (or hedgehog signals) which can be correlated to both the presence of the plaque, and (preoperative) symptoms of the patient. - showing a detectable signal at fluorescence, a relation will be sought between the intensity of the signal and the vulnerability of the plaque (related to previously detected biomarkers and patient symptoms).

—

Secondary

Measure	Time frame
nvt	—

Countries

Netherlands

Outcome results