bowelcancer intestinal cancer
Conditions
Interventions
Monthly measurement CEA from blood sample in the 2 years after curative
resection.
Instead of CEA measurement every 3 months as advised in the current guidelines.
Sponsors
Medisch Spectrum Twente
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: All patients with stage II-III-IV colorectal carcinoma that had curative treatment and are medically fit for metastasectomy. Patients should be above 18 and not mentally incapacitated
Exclusion criteria
Exclusion criteria: Patients not medically fit for metastasectomy Patients with diagnosed syn- or metachronous incurable metastasis at time of inclusion No written informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of patients eligible for curative resection of liver- or lung metastasis | — |
Secondary
| Measure | Time frame |
|---|---|
| Calculation of the optimal threshold values and measurement frequency of CEA The correlation between CEA and helical CT abdomen/thorax: specifically whether the metastasis can be localised when CEA values suggest metastastatic disease. Evaluation of the logistic feasibility of the proposed follow-up scheme | — |
Countries
Netherlands
Outcome results
None listed