Reproducibility of qualitative, semi quantitative and quantitative DCE- MR Imaging in the knee.

Reproducibility of qualitative, semi quantitative and quantitative DCE- MR Imaging in the knee. - not applicable

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30767

Enrollment

Registered

2007-07-12

Start date

2007-02-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic inflammatory arthritis rheumatoid arthritis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: RA-patients: artritis of a knee joint Healthy volunteers: none

Exclusion criteria

Exclusion criteria: RA-patients : claustrofobia, known allergy to gadolineum contrast agent Healty volunteers: 1)history of joint disease 2)claustrofobia, known allergy to gadolineum contrast agent

Design outcomes

Primary

Measure	Time frame
DCE-MRI scans obtained at the two time points will be scored according to the omeract RAMRIS score by DCE-MR color coded shape mapping and by compartmental analysis (quantitative analysis) (appendix B). Correlation between the two time points will be evaluated by the Spearman*s rank correlation coefficient. In addition the change in mean, within patient standard deviation, within patient coefficient of variation and the repeatability will be determined. Differences between healthy individuals and arthritis patients will be evaluated to determine the basal level of enhancement	—

Measure

Time frame

DCE-MRI scans obtained at the two time points will be scored according to the omeract RAMRIS score by DCE-MR color coded shape mapping and by compartmental analysis (quantitative analysis) (appendix B). Correlation between the two time points will be evaluated by the Spearman*s rank correlation coefficient. In addition the change in mean, within patient standard deviation, within patient coefficient of variation and the repeatability will be determined. Differences between healthy individuals and arthritis patients will be evaluated to determine the basal level of enhancement

—

Countries

Netherlands

Outcome results