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Brain Interaction of Cognition and Emotion in Patients with Schizophrenia: experiments in search of a common brain mechanism using functional magnetic resonance imaging (fMRI)

Brain Interaction of Cognition and Emotion in Patients with Schizophrenia: experiments in search of a common brain mechanism using functional magnetic resonance imaging (fMRI) - BICEPS

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON30747
Enrollment
75
Registered
2007-03-20
Start date
2007-03-22
Completion date
Unknown
Last updated
2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psychosis Schizophrenia

Interventions

None.

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: All patients (treated with clozapine or haloperidol or untreated) with a diagnosis of *first episode psychosis*, suggestive for the diagnosis schizophrenia are eligible to participate in the study. Age between 18 and 40 years

Exclusion criteria

Exclusion criteria: Any neurological, cardiovascular, and respiratory diseases; claustrophobia, pregnancy; other relevant psychiatric disorders; MRI contraindications. Subjects will also be excluded when they cannot understand the Dutch language sufficiently to understand the purposes and implications of the experiment.

Design outcomes

Primary

MeasureTime frame
Group differences in pattern or intensity of activation between the group of patients and healthy controls as measured by fMRI. Influence of medication on pattern or intensity of activation in the group of patients with schizophrenia

Secondary

MeasureTime frame
None.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)