Towards a new technique for pre-implantation genetic embryo screening in IVF, pilot phase

Towards a new technique for pre-implantation genetic embryo screening in IVF, pilot phase - Towards a new technique for PGS, pilot

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON30715

Enrollment

435

Registered

2007-06-12

Start date

2007-08-08

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

implantation failure subfertility

Interventions

For enucleation in spare-embryos, a sharp micro-pipette is used to isolate the nucleus and the remaining cytoplasm from a single blastomere and in biopsy-PGS a whole blastomere is isolated using sta

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: standard indication IVF/ICSI written informed consent

Exclusion criteria

Exclusion criteria: Abnormal parental karyotype/genetics if known oocyte donation PESA/MESA two previously failed IVF treatments

Design outcomes

Secondary

Measure	Time frame
Description of a succesful enucleation-PGS procedure	—

Primary

Measure	Time frame
Comparison of successful FISH analyses and the morphology and development of these embryos with biopsy-PGS and control embryos.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)