iron defecient anemia
Conditions
Interventions
Patients in the study group will receive 300 mg intravenous iron sucrose (3
ampuls à 5 ml Venofer) on day 0 and 1 postoperative.
Sponsors
Atrium Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients sceduled for elective total hip or knee arthroplasty with preoperative hemoglobin level above 6.8 mmol/l.
Exclusion criteria
Exclusion criteria: Patients with already threated anemia, patients with hemosiderosis, any active infection, current malignancy, uncontrolled hypertension, operated in 3 weeks before randomisation, having blood transfusions in 3 weeks before randomisation, known hypersensitivity to Venofer or one of its components.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in perioperative parameters of iron metabolism and erythroipoiesis. The main parameter is ret-y which indicates the process of reticylocyte hemoglobinisation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Other parameters are ferritin, transferrin, transferrin receptor and ZPP. Another secundary outcome is perioperative hemoglobin level and amount of allogeneic blood transfusions in both groups. | — |
Countries
Netherlands
Outcome results
None listed